/taking-hormone-supplement
Learn about Pure Encapsulations DHEA dosage, side effects, and cost. Supplement info for informed conversations with your provider.

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Contact UsInformation sourced from manufacturer labeling and publicly available references including NIH Office of Dietary Supplements.
Disclosure: Voshell's Pharmacy is a licensed compounding pharmacy that prepares and sells compounded hormone therapy by prescription. As a provider of products in the hormone health space, our perspective may be influenced by our professional and commercial interests. All brand names and trademarks are the property of their respective owners.
The following dosing information reflects the Pure Encapsulations DHEA product labeling:
According to Pure Encapsulations DHEA product labeling, individuals using prescription hormone therapies or those with hormone-sensitive conditions should consult their healthcare provider before use.

According to Pure Encapsulations DHEA product labeling, avoid use if pregnant, breastfeeding, or trying to conceive. According to Pure Encapsulations DHEA product labeling, individuals with a history of hormone-sensitive cancers should consult their specialist before use. According to Pure Encapsulations DHEA product labeling, individuals with mood disorders should use caution and consult their healthcare provider. According to Pure Encapsulations DHEA product labeling, if you are using prescription hormone replacement therapy, speak with your healthcare provider before adding this supplement.
Very common
Mild
According to Pure Encapsulations DHEA product labeling, some users may notice increased skin oiliness or acne, particularly in those sensitive to androgens. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
1–6 hours
Common
Mild
According to Pure Encapsulations DHEA product labeling, some women may experience changes in hair growth patterns as a result of androgen activity. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
12–48 hours
Occasional
Moderate
According to Pure Encapsulations DHEA product labeling, some users may notice increased irritability, restlessness, or mood changes. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
2–6 hours
Occasional
Mild
According to Pure Encapsulations DHEA product labeling, some users may experience changes in sleep quality or difficulty sleeping, particularly when the supplement is not taken in the morning. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
3–8 hours
Uncommon
Mild
According to Pure Encapsulations DHEA product labeling, some women may experience temporary breast soreness or fullness. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
6–24 hours
Occasional
Mild
According to Pure Encapsulations DHEA product labeling, significant acne, rapid hair loss, or signs of androgen excess are serious labeled warnings associated with DHEA supplementation. Stop use and consult a healthcare provider if these symptoms occur. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
1–3 hours
Need Help Taking This the Right Way?
Quick, caring advice from pharmacists who know these medications inside out.
If you have questions about this dietary supplement, speak with your healthcare provider or pharmacist for guidance based on your individual health needs.

If you miss a dose, take it when you remember — and if it is already close to your next scheduled dose, skip the missed dose. Per the manufacturer's labeling for dosing guidance, do not take extra capsules to make up for a missed dose.
Simply resume your usual routine the next morning.
If more than the recommended amount of Pure Encapsulations DHEA was taken, contact Poison Control at 1-800-222-1222. If a child has ingested this product, seek urgent medical care immediately.

Pure Encapsulations DHEA is a dietary supplement, so insurance generally does not cover it.
These are approximate examples only and actual prices will vary by retailer, location, and time of purchase. According to retailer listings reviewed in early 2026, approximate price ranges included:
Occasional promotions may reduce the cost. These figures are approximate and may no longer reflect current pricing.
Pure Encapsulations DHEA overview: marketed to support energy, mood, and hormone precursor levels. Review uses, benefits, and individual response considerations.