/taking-hormone-supplement
Learn about SMNutrition Progesto-Life Cream dosage, side effects, and cost. Supplement info for informed conversations with your provider.

Not medical advice. Speak with a healthcare professional before using any medication.


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Contact UsInformation sourced from manufacturer labeling and publicly available references including NIH Office of Dietary Supplements.
Disclosure: Voshell's Pharmacy is a licensed compounding pharmacy that prepares and sells compounded hormone therapy by prescription. As a provider of products in the hormone health space, our perspective may be influenced by our professional and commercial interests. All brand names and trademarks are the property of their respective owners.
The following dosing information reflects the SMNutrition Progesto-Life Cream product labeling:
According to SMNutrition Progesto-Life Cream product labeling, if you are using any prescription hormone therapy, consult your healthcare provider before adding this product.

According to SMNutrition Progesto-Life Cream product labeling, avoid use if pregnant, breastfeeding, or trying to conceive unless directed by a healthcare provider. According to SMNutrition Progesto-Life Cream product labeling, individuals with hormone-sensitive conditions such as certain breast or uterine cancers should obtain medical guidance before use. According to SMNutrition Progesto-Life Cream product labeling, consult your healthcare provider before use if you are already using prescription hormone replacement therapy. According to SMNutrition Progesto-Life Cream product labeling, stop use and consult a healthcare provider if you experience unusual bleeding or significant mood changes.
Common
Mild
According to SMNutrition Progesto-Life Cream product labeling, some women may notice gentle breast soreness or fullness during use. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
3–6 hours
Common
Mild
According to SMNutrition Progesto-Life Cream product labeling, mild headaches may occur, particularly during the initial period of use. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
2–4 hours
Common
Mild
According to SMNutrition Progesto-Life Cream product labeling, some users may experience increased fatigue or drowsiness, most notably shortly after application. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
1–3 hours
Uncommon
Moderate
According to SMNutrition Progesto-Life Cream product labeling, some women may notice light spotting or small changes in their menstrual cycle during use. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
6–12 hours
Uncommon
Mild
According to SMNutrition Progesto-Life Cream product labeling, some women may feel mildly more emotional or irritable during the initial period of use. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
2–6 hours
Common
Mild
According to SMNutrition Progesto-Life Cream product labeling, unexpected or significant vaginal bleeding is a serious labeled warning associated with progesterone-containing products. Stop use immediately and consult a healthcare provider if unexpected or unusual bleeding occurs. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
0.5–2 hours
Need Help Taking This the Right Way?
Quick, caring advice from pharmacists who know these medications inside out.
If you have questions about this dietary supplement, speak with your healthcare provider or pharmacist for guidance based on your individual health needs.

If you miss an application, apply it when you remember — and if it is already close to your next scheduled application, skip the missed dose. Per the manufacturer's labeling for dosing guidance, do not double the amount at the next application.
Simply resume your usual routine at the next scheduled time.
If more than the recommended amount of SMNutrition Progesto-Life Cream was applied, contact Poison Control at 1-800-222-1222. If a child has been exposed to this product, seek urgent medical care immediately.

SMNutrition Progesto-Life Cream is an over-the-counter product, so insurance generally does not cover it.
These are approximate examples only and actual prices will vary by retailer, location, and time of purchase. According to retailer listings reviewed in early 2026, approximate price ranges included:
Occasional promotions may reduce the cost. These figures are approximate and may no longer reflect current pricing.
SMNutrition Progesto-Life Cream review: an overview of this OTC topical supplement marketed to support hormonal balance and perimenopausal comfort.