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Learn about Source Naturals Pregnenolone dosage, side effects, warnings, and cost. Educational information for informed conversations with your provider.

Not medical advice. Speak with a healthcare professional before using any medication.


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Contact UsInformation sourced from manufacturer labeling and publicly available references including NIH Office of Dietary Supplements.
Disclosure: Voshell's Pharmacy is a licensed compounding pharmacy that prepares and sells compounded hormone therapy by prescription. As a provider of products in the hormone health space, our perspective may be influenced by our professional and commercial interests. All brand names and trademarks are the property of their respective owners.
The following dosing information reflects Source Naturals Pregnenolone product labeling:
According to Source Naturals Pregnenolone product labeling, do not exceed the recommended serving. Consult your healthcare provider before use, particularly if you are taking other medications or have a hormone-sensitive condition.

According to Source Naturals Pregnenolone product labeling, avoid use if you are pregnant or breastfeeding. According to Source Naturals Pregnenolone product labeling, consult your healthcare provider before use if you take hormone replacement therapy, oral contraceptives, steroids, or mood medications. According to Source Naturals Pregnenolone product labeling, individuals with a history of hormone-sensitive cancers should consult their clinician before use. According to Source Naturals Pregnenolone product labeling, stop use and consult a healthcare provider if you notice unusual mood changes, acne, or cycle irregularities.
Common
Moderate
According to Source Naturals Pregnenolone product labeling, irritability, anxiety, or a sense of restlessness are labeled warnings for this product, particularly at higher serving sizes. Stop use and consult a healthcare provider if these symptoms appear. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
2–6 hours
Common
Mild
According to Source Naturals Pregnenolone product labeling, some users may notice headache when starting or adjusting this supplement. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
2–4 hours
Occasional
Mild
According to Source Naturals Pregnenolone product labeling, some users may experience restlessness or changes in sleep quality. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
4–8 hours
Uncommon
Mild
According to Source Naturals Pregnenolone product labeling, some users may notice mild breast fullness or tenderness. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
12–24 hours
Uncommon
Mild
According to Source Naturals Pregnenolone product labeling, some users may experience increased oil production or breakouts. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
12–24 hours
Rare
Mild
According to Source Naturals Pregnenolone product labeling, a small number of users may report nausea or mild stomach discomfort. Taking this supplement with food may reduce this effect. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
1–3 hours
Need Help Taking This the Right Way?
Quick, caring advice from pharmacists who know these medications inside out.
If you have questions about this dietary supplement, speak with your healthcare provider or pharmacist for guidance based on your individual health needs.

If you miss a dose, take it when you remember — and if it is already close to your next scheduled dose, skip the missed dose. According to Source Naturals Pregnenolone product labeling, do not take extra tablets or capsules to make up for a missed dose.
Simply resume your usual routine the next day. Refer to the manufacturer's labeling for dosing guidance specific to this product.
If more than the recommended amount was taken, contact Poison Control at 1-800-222-1222. If a child has ingested this product, seek urgent medical care immediately.

Source Naturals Pregnenolone is an over-the-counter supplement, so insurance generally does not cover it.
These are approximate examples only and actual prices will vary by retailer, location, and time of purchase. According to retailer listings reviewed in early 2026, approximate price ranges included:
Occasional coupons or store promotions may reduce the cost. These figures are approximate and may no longer reflect current pricing.
Source Naturals Pregnenolone overview and review: marketed to support memory, mood, and energy as a dietary supplement under DSHEA. Individual responses vary.