/taking-hormone-supplement
Learn about Source Naturals Progesterone Cream dosage, side effects, warnings, and cost. Educational information for informed conversations with your provider.

Not medical advice. Speak with a healthcare professional before using any medication.


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Contact UsInformation sourced from manufacturer labeling and publicly available references including NIH Office of Dietary Supplements.
Disclosure: Voshell's Pharmacy is a licensed compounding pharmacy that prepares and sells compounded hormone therapy by prescription. As a provider of products in the hormone health space, our perspective may be influenced by our professional and commercial interests. All brand names and trademarks are the property of their respective owners.
The following dosing information reflects Source Naturals Progesterone Cream product labeling:
According to Source Naturals Progesterone Cream product labeling, do not exceed the recommended serving. Consult your healthcare provider before use, particularly if you take prescription hormones or have an underlying health condition.

According to Source Naturals Progesterone Cream product labeling, avoid use if you have a history of breast cancer, unexplained vaginal bleeding, or active liver disease. According to Source Naturals Progesterone Cream product labeling, consult your healthcare provider before use if you are on prescription hormone replacement therapy. According to Source Naturals Progesterone Cream product labeling, stop use and consult a healthcare provider if you notice new breast tenderness, significant mood changes, or persistent headaches. According to Source Naturals Progesterone Cream product labeling, consult your healthcare provider before use if you take fertility medications or thyroid treatment.
Very common
Mild
According to Source Naturals Progesterone Cream product labeling, breast soreness or fullness is a labeled warning for this product. Stop use and consult a healthcare provider if breast tenderness is persistent or severe. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
4–12 hours
Occasional
Mild
According to Source Naturals Progesterone Cream product labeling, some users may experience mild headaches when beginning use of this product. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
2–6 hours
Common
Mild
According to Source Naturals Progesterone Cream product labeling, some users may notice increased tiredness or drowsiness, particularly after application. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
3–8 hours
Uncommon
Mild
According to Source Naturals Progesterone Cream product labeling, some users may notice mood shifts such as irritability during initial use. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
2–10 hours
Occasional
Mild
According to Source Naturals Progesterone Cream product labeling, some users may experience redness or itching at the application site. Rotating application areas may help reduce this effect. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
1–4 hours
Uncommon
Moderate
According to Source Naturals Progesterone Cream product labeling, spotting or changes in menstrual timing may occur, particularly in perimenopause. Stop use and consult a healthcare provider if bleeding becomes heavy or persistent. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
24–72 hours
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If you have questions about this dietary supplement, speak with your healthcare provider or pharmacist for guidance based on your individual health needs.

If you miss a dose, apply when you remember — and if it is already close to your next scheduled application, skip the missed dose. According to Source Naturals Progesterone Cream product labeling, do not apply extra cream to make up for a missed dose.
Simply resume your usual routine the next day. Refer to the manufacturer's labeling for dosing guidance specific to this product.
If more than the recommended amount was applied, contact Poison Control at 1-800-222-1222. If a child has been exposed to this product, seek urgent medical care immediately.

Source Naturals Progesterone Cream is an over-the-counter product, so insurance generally does not cover it.
These are approximate examples only and actual prices will vary by retailer, location, and time of purchase. According to retailer listings reviewed in early 2026, approximate price ranges included:
Occasional coupons or store promotions may reduce the cost. These figures are approximate and may no longer reflect current pricing.
Source Naturals Progesterone Cream overview: marketed to support hormonal balance and mild cyclical symptoms. Review key facts and DSHEA-compliant supplement information.