How to use Lotrimin (clotrimazole): application instructions per OTC labeling, common side effects, and when to seek medical advice.

Not medical advice. Speak with a healthcare professional before using any medication.


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Information sourced from FDA-approved prescribing information and peer-reviewed medical references.
Per OTC labeling, Lotrimin is for external skin use only. Follow the directions on the product label.

Common
Mild
Per OTC labeling, some people notice mild redness, itching, or burning where Lotrimin is applied.
Per OTC Drug Facts labeling. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
a few minutes to 1 hour
Occasional
Mild
Per OTC labeling, Lotrimin can occasionally make the treated area feel dry, flaky, or slightly tight with repeated use.
Per OTC Drug Facts labeling. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
1–3 hours
Occasional
Mild
Per OTC labeling, a brief, mild stinging or tingling may occur right after application, particularly on sensitive skin.
Per OTC Drug Facts labeling. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
1–5 minutes
Rare
Moderate
Per OTC labeling, the application area may rarely become puffy or tender. Discontinue use if this occurs and consult a healthcare provider.
Per OTC Drug Facts labeling. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
1–2 hours
Uncommon
Moderate
Per OTC labeling, in uncommon cases a new rash or raised bumps can appear, indicating sensitivity to the medication. Discontinue use if this occurs.
Per OTC Drug Facts labeling. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
several hours
Rare
Severe
Per OTC labeling, very rarely, signs of allergy such as intense itching, blistering, or spreading redness may occur. Seek medical attention if these symptoms occur.
Per OTC Drug Facts labeling. If symptoms persist or worsen, stop use and consult a healthcare provider.
Normally lasts for:
several hours to a day
Have questions about compounding? Contact Voshell's Pharmacy — we prepare patient-specific medications pursuant to valid prescriptions from your licensed prescriber.

Per OTC labeling, if you miss an application of Lotrimin, apply it as soon as you remember. If it is almost time for your next scheduled application, return to your regular schedule.
Do not apply double the amount to make up for a missed application.
Per OTC labeling, consistent daily use is important for the medication to work as directed.
Call Poison Control at 1-800-222-1222 immediately if Lotrimin was swallowed or applied in a very large amount.
Per OTC labeling, if swallowed, Lotrimin may cause nausea, vomiting, or abdominal discomfort. Excessive topical application may cause local skin irritation. If symptoms are severe, call 911 or go to the nearest emergency room.

Lotrimin is an over-the-counter medication. Most standard insurance plans do not cover OTC products. FSA/HSA funds may be applicable; verify eligibility with your plan. Pricing information is not a guarantee of cost; contact your pharmacy or retailer for current pricing.
Lotrimin is an over-the-counter medication, so its price is not dependent on insurance coverage. Generic clotrimazole is available at many pharmacies at lower cost than brand-name Lotrimin. Prices vary by formulation, tube size, and retailer. Pricing information is not a guarantee of cost; contact your pharmacy for current pricing.