How to take Zyrtec (cetirizine): dosage guidelines, common side effects, and precautions per OTC labeling for allergy relief.

Not medical advice. Speak with a healthcare professional before using any medication.


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Information sourced from FDA-approved prescribing information and peer-reviewed medical references.
Per OTC labeling, Zyrtec (cetirizine) may be taken with or without food, once daily. Take it at the same time each day for consistent symptom control. Swallow tablets whole; measure liquid formulations with a dosing syringe or cup.

Common
Mild
Per OTC labeling, drowsiness is a recognized adverse effect of cetirizine. Per OTC labeling, avoid driving or operating hazardous machinery until you know how this medication affects you.
Normally lasts for:
6–8 hours
Common
Mild
Per OTC labeling, dry mouth is a recognized adverse effect of cetirizine, related to its mild anticholinergic activity. Adequate hydration may help.
Normally lasts for:
1–3 hours
Common
Mild
Per OTC labeling, fatigue is a recognized adverse effect associated with cetirizine use.
Normally lasts for:
4–6 hours
Common
Mild
Per OTC labeling, headache is a recognized adverse effect associated with cetirizine use.
Normally lasts for:
1–2 hours
Uncommon
Mild
Per OTC labeling, nausea or stomach upset may occur with cetirizine. Taking Zyrtec with food may reduce gastrointestinal effects.
Normally lasts for:
1–3 hours
Uncommon
Mild
Per OTC labeling, dry or irritated eyes may occur as an adverse effect of cetirizine. Lubricating eye drops may provide relief.
Normally lasts for:
1–2 hours
Have questions about compounding? Contact Voshell's Pharmacy — we prepare patient-specific medications pursuant to valid prescriptions from your licensed prescriber.

Per OTC labeling, Zyrtec is taken once daily. If a dose is missed, take it when remembered, as long as it is not close to the time for the next dose. If it is near the time for the next dose, skip the missed dose and resume the regular schedule.
Contact Poison Control immediately at 1-800-222-1222 (U.S.) if you suspect an overdose, especially if a child is involved or if symptoms are present. Call 911 if the person is unresponsive or experiencing a medical emergency.

Zyrtec (cetirizine) is an over-the-counter medication. Most insurance plans do not cover OTC products. Actual costs depend on your specific plan's OTC benefits, if any. FSA/HSA funds may be applicable for eligible OTC purchases. Contact your insurance plan or pharmacy directly for current pricing and coverage information.
Pricing information is subject to change. This is not a guarantee of coverage or cost.
The price of Zyrtec and generic cetirizine varies by retailer, dosage, and package size. Generic cetirizine products are widely available. Contact your local pharmacy or retailer directly for current pricing. FSA/HSA funds may be used for eligible OTC medications.
Pricing information is subject to change and may vary by location and retailer.
https://medlineplus.gov/druginfo/meds/a697038.html
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2ec20ce6-2c9d-4ce2-9e50-1ed8aaef562c
https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/zyrtec-cetirizine-hcl-information
https://www.zyrtec.com/products/zyrtec-tablets