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What to Know About Digest Comfort Blend
Educational overview of Digest Comfort Blend, a compounded preparation from Voshell's Pharmacy that may include digestive enzymes, probiotics, and herbal carminatives.
Not medical advice. Speak with a healthcare professional before using any medication.
Reviewed by:
D. Goren
Head of Content
Updated Nov, 30
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Contact UsWhat Is Digest Comfort Blend
DISCLOSURE: Voshell's Pharmacy is a licensed compounding pharmacy that prepares and sells compounded medications by prescription. As a provider of competing products, our perspective may be influenced by our professional and commercial interests.
Digest Comfort Blend is the name Voshell's Pharmacy uses for compounded preparations that may include digestive enzymes, probiotic strains, and herbal carminatives, prepared in response to a valid prescription from a qualified prescriber. Compounded medications are not reviewed by FDA for safety or effectiveness before dispensing and are prepared by a licensed pharmacist only in response to a valid prescription for an individual patient.
What's inside
Digestive enzymes (amylase, protease, lipase) -- according to the NIH Office of Dietary Supplements, these enzymes are involved in normal breakdown of dietary carbohydrates, proteins, and fats respectively. Probiotic strains such as Lactobacillus and Bifidobacterium -- according to the NIH Office of Dietary Supplements, these organisms are involved in the composition of the intestinal microbiota and play a role in gut microbial balance. Herbal carminatives such as ginger, peppermint, and fennel -- according to the Natural Medicines database, these botanicals have been studied for their role in normal gastrointestinal motility. Some formulations may also include DGL or L-glutamine, which have been studied for their involvement in gastrointestinal mucosal integrity, and prebiotic fiber such as inulin, which is involved in supporting beneficial gut bacteria.
Use, safety, and personalization
- How to take: generally administered with meals; a qualified prescriber should guide dosing for the individual preparation.
- Safety considerations: peppermint-containing formulations may worsen reflux in some individuals; enzyme components may cause gastrointestinal upset in some cases -- discuss your full health history with a qualified prescriber, particularly if pregnant, breastfeeding, or immunocompromised.
- Compounded option: when a commercially available product does not meet an individual patient's needs, a licensed compounding pharmacy may prepare a tailored formulation based on a valid prescription from a qualified prescriber.
This page describes a compounded or supplement preparation for educational purposes. It is not intended to diagnose, treat, cure, or prevent any digestive disease. Persistent or severe GI symptoms should be evaluated by a clinician.
Key Product Features
Digestive Enzymes (Amylase, Protease, Lipase)
- According to the NIH Office of Dietary Supplements, amylase, protease, and lipase are involved in normal breakdown of dietary carbohydrates, proteins, and fats respectively. Inclusion of these enzymes in a compounded preparation does not establish clinical benefit for any disease, condition, or patient outcome.
Probiotic Strains (Lactobacillus and Bifidobacterium)
- According to the NIH Office of Dietary Supplements, Lactobacillus and Bifidobacterium strains are involved in the composition of the intestinal microbiota and play a role in gut microbial balance. Inclusion of these strains in a compounded preparation does not establish clinical benefit for any disease, condition, or patient outcome.
Herbal Carminatives (Ginger, Peppermint, Fennel)
- According to the Natural Medicines database, ginger, peppermint, and fennel are involved in normal gastrointestinal motility and have been studied for their role in normal digestive function. Inclusion of these botanicals in a compounded preparation does not establish clinical benefit for any disease, condition, or patient outcome.
Prebiotic Fiber and Mucosal-Support Nutrients (Inulin, DGL, L-Glutamine)
- According to the NIH Office of Dietary Supplements, inulin is a prebiotic fiber involved in supporting beneficial gut bacteria; DGL (deglycyrrhizinated licorice) and L-glutamine are involved in gastrointestinal mucosal integrity. Inclusion of these nutrients in a compounded preparation does not establish clinical benefit for any disease, condition, or patient outcome.
Contact Us for a Personalized Care Plan
Have questions about compounding? Contact Voshell's Pharmacy — we prepare patient-specific medications pursuant to valid prescriptions from your licensed prescriber.
Do You Need Prescription for Digest Comfort Blend
Do You Need a Prescription for Digest Comfort Blend?
Short answer: Prescription requirements for Digest Comfort Blend depend on the active ingredients and how the formulation is labeled. Most versions combining probiotics, digestive enzymes, and herbal carminatives are available as dietary supplements without a prescription; however, if the formulation includes a prescription-only drug (for example, prescription-strength pancreatic enzymes such as pancrelipase), a valid prescription is required.
- Check the label: If the label reads "Dietary Supplement" or lists probiotic strains, plant-derived enzymes, or botanical ingredients, the product is likely available over the counter. The presence of "Rx only" or a prescription drug name indicates a prescription is required.
- Speak with your prescriber or pharmacist: They may help clarify which formulation is appropriate for your situation, including any interactions or special considerations during pregnancy or other health conditions.
- Compounded preparations: A compounding pharmacy may prepare a customized formulation that is not commercially available. Such preparations are not FDA-reviewed for safety or efficacy prior to dispensing and require a valid prescription issued by a qualified prescriber for an individual patient.
- Consult a qualified prescriber: If you have persistent or complex digestive symptoms, a prescriber evaluation is recommended to determine whether a compounded or prescription-strength preparation is appropriate for your individual needs.
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These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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